98 research outputs found

    The Council\u27s Spirit: Vatican II: The Time for Reconciliation

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    A Characteristic Impulse Toward Excellence

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    Predictive Golf Analytics Versus the Daily Fantasy Sports Market

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    This study examines the different skills necessary for PGA tour players to succeed at specific annual tournaments, in order to create a predictive model for DraftKings PGA contests. The model takes into account data from the PGA Tour ShotLink Intelligence Program. The predictive model is created each week based on past results from the specific tournament in question, with the hope of predicting a group of twenty-five players who should be successful based on their statistical profile. The results of the model are detailed in this paper, which covers the first nine weeks of the 2017 PGA Tour season, with a net profit of $45,070. Despite a positive profit there is not enough information to prove significance, so the model would need to be carried out for many more weeks to be conclusive. Ultimately, the study shows that each PGA Tour course is slightly different, which means certain players should be more successful at certain courses, which is valuable information for predicting future outcomes

    CELLULAR AND CIRCUIT PROPERTIES OF SLOW OSCILLATIONS IN THE THALAMIC RETICULAR NUCLEUS

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    During sleep, neurons in the thalamic reticular nucleus (TRN) generate distinct types of oscillatory activity. While the reciprocal synaptic circuits between TRN and sensory thalamic nuclei underlie the generation of sleep spindles, the mechanisms regulating slow (\u3c1 \u3eHz) forms of thalamic oscillations are poorly understood. Under in vitro conditions, in the absence of synaptic inputs, TRN neurons can generate slow oscillations in a cell-intrinsic manner. Activation of postsynaptic Group 1 metabotropic glutamate receptors (mGluR) leads to long-lasting plateau potentials thought to be mediated by both T-type calcium currents and calcium-activated nonselective cation currents (ICAN). However, the identity of ICAN and the possible contribution of thalamic circuits to slow rhythmic activity remain unclear. Using intracellular recordings of neurons in thalamic slices derived from adult male and female mice, I recorded slow forms of rhythmic activity in TRN neurons. Slow oscillations were driven by fast glutamatergic inputs from thalamic relay neurons, but did not require postsynaptic mGluR activation. For a significant minority of TRN neurons (33%), synaptic inputs or brief depolarizing current steps led to plateau potentials and persistent firing (PF), and in turn, resulted in persistent synaptic inhibition in postsynaptic relay neurons of the ventrobasal thalamus (VB). Pharmacological approaches indicated that plateau potentials were triggered by calcium influx through T-type calcium channels and mediated by calcium and voltage-dependent transient receptor potential melastatin 4 (TRPM4) channels. Taken together, my results suggest that thalamic circuits can generate slow oscillatory activity, mediated by an interplay of TRN-VB synaptic circuits that generate rhythmicity and TRN cell-intrinsic mechanisms that control PF and oscillation frequency

    The Jury System in Contemporary Ireland: In the Shadow of a Troubled Past

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    Jackson et al discuss the distinctive features of criminal trial by jury in Ireland, both north and south, to explain how the jury continues to survive within modern Ireland and how it also has managed to decline in significance

    Subrogation Against Banks on Forged Checks

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    Auditory masking in spontaneously hypertensive rat: An examination of the continuum of impulsivity

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    Signal detection theory can measure impulsive behavior. To further examine this paradigm, the researcher attempted to replicate previous findings with more experimental control and examine impulsive behaviors in a putative model of Attention Deficit/Hyperactivity Disorder, the Spontaneously Hypertensive Rat. Four strains of rats attempted to discriminate between the presence and absences of a 3 kHz tone within a 5-6 kHz masker; however, only one rat reached stabilization. To aid in training and reduce difficulty of the task, the researcher presented the rat wit forced-choice trials. Although the additional training increased their variability of correct responses, rats were unable to reach the stability criterion. The complexity of the task could account for low stabilization rates. The methodology could be used to create experimental designs to further investigate impulsivity through auditory discrimination using simpler tasks

    Death Penalty

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